The isolated perfusion mammalian heart preparation is as a tool for studying heart biology (langendorff and coronaryfilw.cf). It has been one of the most widely adopted models of mammalian cardiophysiology for basic and pre-clinical drug research.

It can be used for direct constant circulation. By connecting with a Peristaltic pump, it can do constant-rate circulation experiment.

The Langendorff technique is well suited to many different models of cardiac disease and dysfunction.